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WCA-814

Product Specifications

Target

Androgen Receptor

Related Pathways

Endocrinology/Hormones

Bioactivity

WCA-814, an androgen receptor (AR) antagonist-Hsp90 inhibitor conjugate, induces degradation of both full-length and AR-V7, exhibiting cytotoxic effects in prostatic cancer cells with half maximal inhibitory concentrations (IC50) of 171.2 nM and 26.5 nM for LNCaP and 22Rv1 cells, respectively [1].

Molecular Formula

C46H53ClN10O5

Molecular Weight

861.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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