HIF-2α-IN-9
Product Specifications
CAS Number
2648334-36-3
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Chromatin/Epigenetic, Metabolism
Bioactivity
HIF-2α-IN-9 (compound 35r) is an HIF-2α inhibitor that effectively suppresses VEGF-A with an IC50 of 305 nM, modulates growth-promoting genes within tumor cells, and reactivates macrophage-mediated tumor immunity [1].
Smiles
S(C)(=O)(=O)C1=C2C(=C(OC[C@@H](C(F)(F)F)C)S1)CC(F)(F)[C@H]2O
Molecular Formula
C12H13F5O4S2
Molecular Weight
380.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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