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HIF-2α-IN-9

Product Specifications

CAS Number

2648334-36-3

Target

HIF/HIF Prolyl-Hydroxylase

Related Pathways

Chromatin/Epigenetic, Metabolism

Bioactivity

HIF-2α-IN-9 (compound 35r) is an HIF-2α inhibitor that effectively suppresses VEGF-A with an IC50 of 305 nM, modulates growth-promoting genes within tumor cells, and reactivates macrophage-mediated tumor immunity [1].

Smiles

S(C)(=O)(=O)C1=C2C(=C(OC[C@@H](C(F)(F)F)C)S1)CC(F)(F)[C@H]2O

Molecular Formula

C12H13F5O4S2

Molecular Weight

380.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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