HIV-1 inhibitor-58
Product Specifications
Target
Others|||Reverse Transcriptase|||HIV Protease|||Cytochromes P450
Related Pathways
Metabolism|||Microbiology/Virology|||Proteases/Proteasome|||Others
Bioactivity
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type strain IIIB and NNRTI-resistant strains like K103N and E138K in MT-4 cells at an EC50 of less than 50 nM. Additionally, it inhibits CYP2C9 and CYP2C19 with IC50 values of 2.06 ?M and 1.91 ?M, respectively. This compound is utilized in HIV infection research [1].
Molecular Formula
C26H24N6O2
Molecular Weight
452.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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