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SHP2-IN-22

Product Specifications

CAS Number

2802453-88-7

Target

Ras|||Others|||Phosphatase|||Kras

Related Pathways

Others|||MAPK|||Metabolism

Bioactivity

SHP2-IN-22, a potent SHP2 allosteric inhibitor, exhibits an IC50 value of 17.7 nM and effectively suppresses proliferation, migration, and invasion in MIA PaCa-2 pancreatic cancer cells. This compound is utilized in the study of Kirsten rat sarcoma viral oncogene (KRAS) mutant cancer research [1].

Smiles

NC=1C(=NC=C(N1)N2CCN(C(NC3=CC(OC)=C(C#N)C=C3)=N)CC2)C4=C(Cl)C(Cl)=CC=C4

Molecular Formula

C23H22Cl2N8O

Molecular Weight

497.38

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/123792051975225571/T78896

Available Sizes

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