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NLRP3-IN-21

Product Specifications

CAS Number

2956791-61-8

Target

NOD-like Receptor (NLR)

Related Pathways

Immunology/Inflammation

Bioactivity

NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome with anti-inflammatory properties, suppressing inflammasome activation and pyroptosis by inhibiting gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly [1].

Smiles

C(C)(C)C=1N2C(=CC3=C2C=C(Cl)S3)C(=O)N(CC=4OC(=NN4)C5=C(Cl)N=C(C(F)(F)F)C=C5)N1

Molecular Formula

C20H13Cl2F3N6O2S

Molecular Weight

529.32

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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