NLRP3-IN-21
Product Specifications
CAS Number
2956791-61-8
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome with anti-inflammatory properties, suppressing inflammasome activation and pyroptosis by inhibiting gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly [1].
Smiles
C(C)(C)C=1N2C(=CC3=C2C=C(Cl)S3)C(=O)N(CC=4OC(=NN4)C5=C(Cl)N=C(C(F)(F)F)C=C5)N1
Molecular Formula
C20H13Cl2F3N6O2S
Molecular Weight
529.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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