MTX-241F
Product Specifications
Target
EGFR|||PI3K
Related Pathways
PI3K/Akt/mTOR signaling|||JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors
Bioactivity
MTX-241F, a selective small molecule inhibitor, targets members of the EGFR and PI3 kinase families. It penetrates the blood-brain barrier, providing long-term tumor growth control and exhibits radiosensitizing activity in patient-derived DIPG neurospheres, potentially beneficial for studying diffuse intrinsic pontine glioma (DIPG) [1].
Molecular Formula
C20H14ClFN6
Molecular Weight
392.82
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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