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TWIK-1/TREK-1-IN-2

Product Specifications

CAS Number

1440532-32-0

Target

Potassium Channel

Related Pathways

Membrane transporter/Ion channel

Bioactivity

TWIK-1/TREK-1-IN-2 (Compound 2g) serves as an inhibitor of both TWIK-1 and TREK-1, targeting the TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50 values of 10.13 μM and 15.5 μM, respectively; additionally, it exhibits antidepressant properties [1].

Smiles

C([C@@H](COC1=CC=C(C(F)(F)F)C=C1)O)N2CCC(CC2)N3CCCCC3

Molecular Formula

C20H29F3N2O2

Molecular Weight

386.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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