Anticancer agent 157
Product Specifications
Target
Caspase, Apoptosis, NO Synthase
Related Pathways
Apoptosis, Immunology/Inflammation, Proteases/Proteasome
Bioactivity
Anticancer Agent 157 (compound 15) is a nitric oxide (NO) inhibitor with IC50 values of 0.62 μg/mL, exhibiting both anti-inflammatory and anticancer effects. It interacts with inducible NO synthase (iNOS) and caspase 8, which facilitates apoptosis through nuclear fragmentation and chromatin condensation. Additionally, Anticancer Agent 157 effectively inhibits HT29 colon cancer cells (IC50 =2.45 μg/mL), Hep-G2 liver cancer cells (IC50 =3.25 μg/mL), and B16-F10 murine melanoma cells (IC50 =3.84 μg/mL) [1].
Molecular Formula
C14H20O2
Molecular Weight
220.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
QP11739-20ug 20ug
Recombinant Human ECHS1 Protein, His, E.coli-20ug
Sign In for Pricing
View Details 
463108-01 5 mg
Propylene Glycol 2-β-Glucopyranosiduronic Acid Benzyl Ester 2,3,4-Triacetate Ammonium Salt
Sign In for Pricing
View Details 463108-02 10 mg
Propylene Glycol 2-β-Glucopyranosiduronic Acid Benzyl Ester 2,3,4-Triacetate Ammonium Salt
Sign In for Pricing
View Details 040026-ML405 100 µL
PIGH, NT (PIGH, Phosphatidylinositol N-acetylglucosaminyltransferase subunit H, Phosphatidylinositol-glycan biosynthesis class H protein) (MaxLight 405) discontinued
Sign In for Pricing
View Details