MET/PDGFRA-IN-2
Product Specifications
Target
C-Met/HGFR, Apoptosis, PDGFR
Related Pathways
Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors
Bioactivity
MET/PDGFRA-IN-2 (compound 8h) is an inhibitor of MET and PDGFRA proteins that promotes apoptosis and impedes proliferation of MET-positive cells with IC50 values of 9.7, 6.1, 12.0, 11.5, 8.6, and 34.4 μM for AsPc-1, EBC-1, MKN-45, Mia-Paca-2, HT-29, and K562 cells, respectively [1].
Molecular Formula
C29H29N7O
Molecular Weight
491.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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