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Nrf2-IN-3

Product Specifications

CAS Number

6325-13-9

Target

Nrf2|||ROS

Related Pathways

Immunology/Inflammation

Purity

0.9807

Bioactivity

Nrf2-IN-3 is a mKEAP1-selective NRF2 inhibitor that selectively binds KEAP1 mutants and restores their NRF2 inhibitory function by repairing the disrupted KEAP1/NRF2 interaction, and selectively sensitizes cisplatin in xenografts of mouse mKEAP1 cancer cells.

Smiles

O=C(NN=CC=1C=CC=CC1O)CCCSCCCC(=O)NN=CC=2C=CC=CC2O

Molecular Formula

C22H26N4O4S

Molecular Weight

442.53

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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