Nrf2-IN-3
Product Specifications
CAS Number
6325-13-9
Target
Nrf2|||ROS
Related Pathways
Immunology/Inflammation
Purity
0.9807
Bioactivity
Nrf2-IN-3 is a mKEAP1-selective NRF2 inhibitor that selectively binds KEAP1 mutants and restores their NRF2 inhibitory function by repairing the disrupted KEAP1/NRF2 interaction, and selectively sensitizes cisplatin in xenografts of mouse mKEAP1 cancer cells.
Smiles
O=C(NN=CC=1C=CC=CC1O)CCCSCCCC(=O)NN=CC=2C=CC=CC2O
Molecular Formula
C22H26N4O4S
Molecular Weight
442.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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