Akt/NF-κB/MAPK-IN-1

Akt/NF-κB/MAPK-IN-1 (compound 2m) is a potent, orally active inhibitor of NO with an IC50 of 7.70 μM and low toxicity, exhibiting anti-inflammatory effects by blocking the Akt/NF-κB and MAPK signaling pathways [1].