IHMT-PI3K-455
Product Specifications
Target
PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
IHMT-PI3K-455 (Compound 15u) is a potent, selective PI3Kγ/δ dual inhibitor with IC50 values of 7.1 nM for PI3Kγ and 0.57 nM for PI3Kδ, exhibiting oral activity. This compound inhibits AKT phosphorylation and promotes tumor regression by recruiting and activating CD8+ T cells. It is utilized in cancer research [1].
Molecular Formula
C26H21F2N7O3
Molecular Weight
517.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1249885-01 0.02 mg (E-Coli)
Recombinant Shewanella pealeana Elongation factor Tu (tuf1)
Sign In for Pricing
View Details MBS1249885-02 0.02 mg (Yeast)
Recombinant Shewanella pealeana Elongation factor Tu (tuf1)
Sign In for Pricing
View Details