JNK2-IN-1
Product Specifications
Target
JNK
Related Pathways
MAPK
Bioactivity
JNK2-IN-1 (Compound J27), a selective JNK2 inhibitor with a dissociation constant (Kd) of 79.2 μM, exhibits anti-inflammatory effects by attenuating TNF-α and IL-6 secretion via inhibition of the NF-κB/MAPK pathway. It effectively mitigates symptoms associated with LPS-induced acute lung injury (ALI) and sepsis [1].
Molecular Formula
C30H26N4O5
Molecular Weight
522.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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