JT002
Product Specifications
CAS Number
2238820-43-2
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
JT002 is an orally active NLRP3 inflammasome inhibitor that decreases the production of NLRP3-dependent proinflammatory cytokines (such as IL-1β, IL-1α, IL-18) and pyroptosis, as well as inhibits the formation of the NLRP3 inflammasome complex. Additionally, JT002 mitigates airway hyperresponsiveness and airway neutrophilia in mice [1].
Smiles
N(C(NS(=O)(=O)C1=C2N(N=C1)C[C@H](OC)CO2)=O)C3=C4C(=CC5=C3CCC5)CCC4
Molecular Formula
C20H24N4O5S
Molecular Weight
432.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15313203 1 Vial
Lentiviral human CASS4 shRNA (UAS) - Lentiviral human CASS4 shRNA (UAS, RFP) (100)
Sign In for Pricing
View Details 