NDNA3
Product Specifications
Target
HSP|||Potassium Channel
Related Pathways
Membrane transporter/Ion channel|||Metabolism|||Cytoskeletal Signaling
Bioactivity
NDNA3 (compound 14) selectively inhibits Hsp90? with an IC50 of 0.51 ?M, demonstrating low membrane permeability and minimal toxicity to Ovcar-8 and MCF-10A cells, with IC50 values of 12.66 ?M and 11.72 ?M respectively. It stabilizes hERG channel maturation without eliciting a heat shock response or degrading Hsp90?-dependent client proteins [1].
Molecular Formula
C28H32N2O3S
Molecular Weight
476.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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