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NDNA3

Product Specifications

Target

HSP|||Potassium Channel

Related Pathways

Membrane transporter/Ion channel|||Metabolism|||Cytoskeletal Signaling

Bioactivity

NDNA3 (compound 14) selectively inhibits Hsp90? with an IC50 of 0.51 ?M, demonstrating low membrane permeability and minimal toxicity to Ovcar-8 and MCF-10A cells, with IC50 values of 12.66 ?M and 11.72 ?M respectively. It stabilizes hERG channel maturation without eliciting a heat shock response or degrading Hsp90?-dependent client proteins [1].

Molecular Formula

C28H32N2O3S

Molecular Weight

476.63

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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