NDNA4
Product Specifications
Target
Potassium Channel, HSP
Related Pathways
Membrane transporter/Ion channel, Metabolism, Cytoskeletal Signaling
Bioactivity
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM) with permanent charge and low membrane permeability. It demonstrates minimal cytotoxicity against Ovcar-8 and MCF-10A cell lines (IC50 >100 μM) and maintains hERG channel maturation without triggering a heat shock response or degrading Hsp90α-dependent client proteins [1].
Molecular Formula
C31H35F3N2O5S
Molecular Weight
604.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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