BChE/HDAC6-IN-1
Product Specifications
CAS Number
2925457-27-6
Target
HDAC, Cholinesterase (ChE)
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic, Neuroscience
Bioactivity
BChE/HDAC6-IN-1 is a dual BChE/HDAC6 inhibitor exhibiting potent and selective inhibition with IC50 values of 4 nM for BChE and 8.9 nM for HDAC6. It demonstrates efficacy in alleviating cognitive deficits in an Aβ1–42-induced mouse model, indicating its potential utility in Alzheimer's disease research [1].
Smiles
C(N(CC)CC)C1=C(CNC(=O)C2=CC(NC(=O)C3=CC(NC(CCCCCCC(NO)=O)=O)=CC=C3)=CC=C2)C=CC=C1
Molecular Formula
C34H43N5O5
Molecular Weight
601.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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