MY-673
Product Specifications
CAS Number
2944459-96-3
Target
Apoptosis|||Others|||ERK|||Microtubule Associated|||TGF-beta/Smad
Related Pathways
Cytoskeletal Signaling|||Stem Cells|||Apoptosis|||Others|||MAPK
Bioactivity
MY-673, a colchicine binding site inhibitor (CBSI), impedes tubulin polymerization and disrupts the ERK signaling pathway, consequently modulating SMAD4 protein expression in the TGF-?/SMAD pathway. This compound effectively reduces cell proliferation and migration while inducing apoptosis in both in vivo and in vitro settings [1].
Smiles
O=C1CN(C=2C(=CC(OC)=CC2)N1)C=3C=4C(OC(=O)C3)=CC=CC4
Molecular Formula
C18H14N2O4
Molecular Weight
322.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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