J-1048
Product Specifications
CAS Number
2374772-60-6
Target
ALK|||Others
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Others
Bioactivity
J-1048, an activin receptor-like kinase 5 (ALK5) inhibitor, effectively suppresses TAA-induced liver fibrosis in mice through specific inhibition of the TGF-?/Smad signaling pathway [1].
Smiles
C(C(NC1=CC(F)=CC=C1)=S)N2C=C(C(=N2)C=3N=C(C)C=CC3)C4=CC=5C(C=C4)=NSN5
Molecular Formula
C23H17FN6S2
Molecular Weight
460.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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