What is the catalog number for RIPK3-IN-3?

The catalog number for RIPK3-IN-3 is T78784.

What sizes are available for RIPK3-IN-3?

RIPK3-IN-3 is available in the following size(s): 5 mg, 50 mg.

How many pack sizes does RIPK3-IN-3 come in?

RIPK3-IN-3 is available in 2 different pack sizes.

Is RIPK3-IN-3 in stock?

RIPK3-IN-3 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RIPK3-IN-3?

RIPK3-IN-3 is manufactured by Molfinity.

What is the estimated delivery time for RIPK3-IN-3?

Estimated delivery time for RIPK3-IN-3 is approximately 10 business day(s), depending on your location.

RIPK3-IN-3

Product Specifications

Target

Others, MLK, RIP kinase

Related Pathways

Apoptosis, NF-κB, Others, MAPK

Bioactivity

RIPK3-IN-3 (compound 20) is a selective RIPK3 inhibitor with a potent IC50 value of 10 nM, effectively blocking RIPK3-mediated phosphorylation of MLKL, preventing oligomerization and necroptosis induction. Moreover, RIPK3-IN-3 suppresses CXCL5 secretion and impedes AsPC-1 cell migration and invasion [1].