RIPK3-IN-3
Product Specifications
Target
Others, MLK, RIP kinase
Related Pathways
Apoptosis, NF-κB, Others, MAPK
Bioactivity
RIPK3-IN-3 (compound 20) is a selective RIPK3 inhibitor with a potent IC50 value of 10 nM, effectively blocking RIPK3-mediated phosphorylation of MLKL, preventing oligomerization and necroptosis induction. Moreover, RIPK3-IN-3 suppresses CXCL5 secretion and impedes AsPC-1 cell migration and invasion [1].
Molecular Formula
C16H11N5S
Molecular Weight
305.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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