PROTAC BTK Degrader-6
Product Specifications
CAS Number
2767204-39-5
Target
PROTACs, BTK
Related Pathways
Angiogenesis, PROTAC, Tyrosine Kinase/Adaptors
Bioactivity
PROTAC BTK Degrader-6 (Compound 15), with a DC50 of 3.18 nM, exhibits anti-inflammatory properties by inhibiting NF-κB activation and suppressing the expression of pro-inflammatory cytokines such as IL-1β and IL-6 [1].
Smiles
NC1=C2C(=NN(C2=NC=N1)C3CCN(C(CN4CCN(CC5CN(C5)C=6C=C7C(=CC6)C(=O)N(C7=O)C8C(=O)NC(=O)CC8)CC4)=O)CC3)C9=CC=C(OC%10=CC=CC=C%10)C=C9
Molecular Formula
C45H47N11O6
Molecular Weight
837.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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