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Vem-L-Cy5

Product Specifications

Target

Raf

Related Pathways

MAPK

Bioactivity

Vem-L-Cy5 (compound 3), a Vemurafenib-based BRAF inhibitor conjugated with the near-infrared (NIR) fluorophore cyanine-5 (Cy5), selectively targets the BRAF V600E mutation and inhibits MEK phosphorylation. This compound demonstrates cell permeability and has been shown to inhibit the growth of various cancer cell types [1].

Smiles

CC(C1=C(N/2CCCCCC(NCCOCCOCC(NC3=CC=C(C4=CN=C(NC=C5C(C6=C(F)C=CC(NS(=O)(CCC)=O)=C6F)=O)C5=C4)C=C3)=O)=O)C=CC=C1)(C)C2=C/C=C/C=C/C7=[N+](C)C(C=CC=C8)=C8C7(C)C.FC(F)(F)C([O-])=O

Molecular Formula

C63H68F5N7O9S

Molecular Weight

1194.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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