Vem-L-Cy5
Product Specifications
Target
Raf
Related Pathways
MAPK
Bioactivity
Vem-L-Cy5 (compound 3), a Vemurafenib-based BRAF inhibitor conjugated with the near-infrared (NIR) fluorophore cyanine-5 (Cy5), selectively targets the BRAF V600E mutation and inhibits MEK phosphorylation. This compound demonstrates cell permeability and has been shown to inhibit the growth of various cancer cell types [1].
Smiles
CC(C1=C(N/2CCCCCC(NCCOCCOCC(NC3=CC=C(C4=CN=C(NC=C5C(C6=C(F)C=CC(NS(=O)(CCC)=O)=C6F)=O)C5=C4)C=C3)=O)=O)C=CC=C1)(C)C2=C/C=C/C=C/C7=[N+](C)C(C=CC=C8)=C8C7(C)C.FC(F)(F)C([O-])=O
Molecular Formula
C63H68F5N7O9S
Molecular Weight
1194.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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