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HDAC-IN-60

Product Specifications

CAS Number

2944459-58-7

Target

Apoptosis, HDAC

Related Pathways

Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair

Bioactivity

HDAC-IN-60 (compound 21a), a potent histone deacetylase (HDAC) inhibitor, promotes intracellular reactive oxygen species (ROS) production, induces DNA damage, arrests the cell cycle at the G2/M phase, and triggers mitochondria-related apoptotic pathways, leading to cell apoptosis [1].

Smiles

O(C)C1=C(OC)C=C(CCC2=CC(NCC(NO)=O)=C(OC)C=C2)C=C1OC

Molecular Formula

C20H26N2O6

Molecular Weight

390.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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