HDAC-IN-59
Product Specifications
CAS Number
2944459-43-0
Target
Apoptosis, HDAC
Related Pathways
Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair
Bioactivity
HDAC-IN-59 (compound 13a), a potent histone deacetylase (HDAC) inhibitor, enhances intracellular reactive oxygen species (ROS) production, induces DNA damage, arrests the cell cycle at the G2/M phase, and triggers the mitochondrial apoptotic pathway, leading to cell apoptosis [1].
Smiles
O(C)C1=C(OC)C=C(CCC2=CC(OCC(NO)=O)=C(OC)C=C2)C=C1OC
Molecular Formula
C20H25NO7
Molecular Weight
391.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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