NF-?B-IN-10
Product Specifications
Target
NF-?B
Related Pathways
NF-?B
Bioactivity
NF-?B-IN-10 (compound E1) is an NF-?B inhibitor that mitigates heart failure symptoms by modulating the Nrf2/NF-?B signaling pathway, alleviating oxidative stress and inflammation. It suppresses LPS-induced NO production and downregulates iNOS and COX-2 expression in RAW264.7 cells, showing potential for cardiovascular disease research [1].
Molecular Formula
C26H30N2O4
Molecular Weight
434.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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