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NF-?B-IN-10

Product Specifications

Target

NF-?B

Related Pathways

NF-?B

Bioactivity

NF-?B-IN-10 (compound E1) is an NF-?B inhibitor that mitigates heart failure symptoms by modulating the Nrf2/NF-?B signaling pathway, alleviating oxidative stress and inflammation. It suppresses LPS-induced NO production and downregulates iNOS and COX-2 expression in RAW264.7 cells, showing potential for cardiovascular disease research [1].

Molecular Formula

C26H30N2O4

Molecular Weight

434.53

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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