HIV-1 inhibitor-57
Product Specifications
CAS Number
2745197-24-2
Target
HIV Protease, Others
Related Pathways
Microbiology/Virology, Others, Proteases/Proteasome
Bioactivity
HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficacy by forming supplementary interactions with residues surrounding the binding site in the HIV-1 reverse transcriptase (RT) [1].
Smiles
FC1=C(C=CC(NC=2N=C(OC3=C(C)C=C(/C=C/C#N)C=C3C)C=CN2)=C1)N4CCS(=O)(=O)CC4
Molecular Formula
C25H24FN5O3S
Molecular Weight
493.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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