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Smurf1-IN-1

Product Specifications

CAS Number

1824708-03-3

Target

E1/E2/E3 Enzyme

Related Pathways

Ubiquitination

Bioactivity

Smurf1-IN-1, a selective E3 ubiquitin protein ligase 1 (SMURF1) inhibitor, exhibits oral activity with an IC50 of 92 nM and demonstrates considerable efficacy in a rat model of pulmonary hypertension [1].

Smiles

O=C(C1=C(C)N(C2=CC=C(C3CC3)C=C2Cl)N=N1)NC4=C(C)N(C)N(C5CCCCC5)C4=O

Molecular Formula

C24H29ClN6O2

Molecular Weight

468.98

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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