Smurf1-IN-1
Product Specifications
CAS Number
1824708-03-3
Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Bioactivity
Smurf1-IN-1, a selective E3 ubiquitin protein ligase 1 (SMURF1) inhibitor, exhibits oral activity with an IC50 of 92 nM and demonstrates considerable efficacy in a rat model of pulmonary hypertension [1].
Smiles
O=C(C1=C(C)N(C2=CC=C(C3CC3)C=C2Cl)N=N1)NC4=C(C)N(C)N(C5CCCCC5)C4=O
Molecular Formula
C24H29ClN6O2
Molecular Weight
468.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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