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COX-2-IN-31

Product Specifications

Target

COX

Related Pathways

Neuroscience|||Immunology/Inflammation

Bioactivity

COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 ?M), and also inhibits transmembrane hCA IX (Ki=48.9 nM) and hCA XII (Ki=5.8 nM), demonstrating anti-inflammatory and analgesic activity [1].

Molecular Formula

C17H16N6O4S

Molecular Weight

400.41

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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