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PTP1B/AKR1B1-IN-2

Product Specifications

Target

Phosphatase, Reductase

Related Pathways

Metabolism, Endocrinology/Hormones

Bioactivity

PTP1B/AKR1B1-IN-2 (Compound 7f) is a potent inhibitor targeting both PTP1B and AKR1B1 with IC50 values of 3.2 and 2.1 μM, respectively, and K i values of 4.0 and 0.9 μM. This compound acts as an insulin mimetic and enhances glucose uptake in murine C2C12 myoblasts, making it useful for Type 2 diabetes mellitus (T2DM) research [1].

Molecular Formula

C23H23NO4S2

Molecular Weight

441.56

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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