HAChE-IN-1
Product Specifications
Target
Cholinesterase (ChE) |||Others|||Microtubule Associated
Related Pathways
Neuroscience|||Others|||Cytoskeletal Signaling
Bioactivity
HAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), with an inhibition concentration half-maximum (IC50) of 1.09 ?M, and inhibits tau-oligomerization with an effective concentration half-maximum (EC50) of 2.71 ?M as determined by a cellular tau fluorescence resonance energy transfer (FRET) assay [1].
Molecular Formula
C22H24N4O
Molecular Weight
360.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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