HPK1-IN-35
Product Specifications
CAS Number
2935903-77-6
Target
Others, MAPK
Related Pathways
Others, MAPK
Bioactivity
HPK1-IN-35 is a potent, selective inhibitor of HPK1, demonstrating an IC50 value of 3.5 nM. This compound reduces p-SLP76 expression and facilitates the secretion of IL-2 [1].
Smiles
N(C1=C2C(=CNC2=NC(NC3=C(OC)C=C4C(=C3)CN(C)CC4)=N1)C=5C=CC=NC5)C6=C(S(N(C)C)(=O)=O)C=CC=C6
Molecular Formula
C30H32N8O3S
Molecular Weight
584.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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