TH-Z835
Product Specifications
CAS Number
2766209-50-9
Target
Apoptosis, Ras
Related Pathways
MAPK, GPCR/G Protein, Apoptosis
Bioactivity
TH-Z835 is a mutant-selective KRAS (G12D) inhibitor with an IC50 of 1.6 μM.This compound inhibits mantGMPPNP/GPPNP exchange and GPPNP/mantGMPPNP exchange.
Smiles
O(C[C@H]1N(C)CCC1)C2=NC(=C3C(CN(CC3)C=4C5=C(C=CC4)C=CC=C5C)=N2)N6CC7NC(C6)CC7
Molecular Formula
C30H38N6O
Molecular Weight
498.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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