TH-Z835

Product Specifications

CAS Number

2766209-50-9

Target

Apoptosis|||Ras

Related Pathways

MAPK|||GPCR/G Protein|||Apoptosis

Bioactivity

TH-Z835 is a mutant-selective KRAS (G12D) inhibitor with an IC50 of 1.6 ?M.This compound inhibits mantGMPPNP/GPPNP exchange and GPPNP/mantGMPPNP exchange.

Smiles

O(C[C@H]1N(C)CCC1)C2=NC(=C3C(CN(CC3)C=4C5=C(C=CC4)C=CC=C5C)=N2)N6CC7NC(C6)CC7

Molecular Formula

C30H38N6O

Molecular Weight

498.66

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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