Glecirasib
Product Specifications
CAS Number
2657613-87-9
Target
Kras|||Ras
Related Pathways
MAPK|||GPCR/G Protein
Purity
>99.99%
Bioactivity
Glecirasib (JAB-21822) is an orally active KRAS G12C inhibitor that selectively binds to and inhibits the activity of KRAS G12C mutants, thereby inhibiting KRAS G12C-dependent signaling. In animal models, KRAS G12C inhibitor 36 showed a favorable safety profile and potential to inhibit tumor growth.
Smiles
N#CC=1C(=O)N(C=2N=C(C(Cl)=CC2C1N3CCN(C(=O)C=C)CC3)C=4C(F)=C(F)C(F)=C(F)C4N)C=5C(=NC=CC5C)C(C)C
Molecular Formula
C31H26ClF4N7O2
Molecular Weight
640.03
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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