Clezutoclax
Product Specifications
CAS Number
1949843-71-3
Target
Bcl-2 Family|||Drug-Linker Conjugates for ADC|||ADC Cytotoxin
Related Pathways
Apoptosis|||Antibody-drug Conjugate/ADC Related
Bioactivity
Clezutoclax, a potent Bcl-XL inhibitor, serves as an effective payload for the synthesis of antibody-drug conjugates (ADCs) [1].
Smiles
C(C12CC3(OCCN(C(OCC4=C(CC[C@@H]5O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]5O)C=C(NC([C@@H](NC([C@@H](NC(CN6[C@H](COCCS(=O)(=O)O)C[C@@H](C6=O)N7C(=O)C=CC7=O)=O)[C@H](C)C)=O)C)=O)C=C4)=O)CC[C@@H](CO)O)CC(C)(C1)CC(C)(C2)C3)N8C(C)=C(C=N8)C9=C(C(O)=O)N=C(C=C9)N%10CC%11=C(C(NC%12=NC=%13C(S%12)=CC=CC%13)=O)C=CC=C%11CC%10
Molecular Formula
C83H102N12O24S2
Molecular Weight
1715.89
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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