APPA
Product Specifications
CAS Number
100750-39-8
Target
Reductase, Apoptosis
Related Pathways
Apoptosis, Metabolism, Endocrinology/Hormones
Bioactivity
APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of the polyol pathway. This compound shows promise for research into diabetic nephropathy (DN) [1].
Smiles
C(C)(=O)N1C(=CC(OC(C)=O)=C1)C2=CC=CC=C2
Molecular Formula
C14H13NO3
Molecular Weight
243.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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