Anticancer agent 164
Product Specifications
CAS Number
2235393-30-1
Target
Apoptosis|||MEK|||PI3K
Related Pathways
PI3K/Akt/mTOR signaling|||Apoptosis|||MAPK
Bioactivity
CML-IN-1, also known as compound 7 and compound 4, is a potent anticancer agent that demonstrates a strong induced-apoptosis effect in the human chronic myeloid leukemia (CML) cell line K562. It diminishes protein phosphorylation within the PI3K/Akt signaling pathway to exert its effects and suppresses cell proliferation through the inhibition of the MEK/ERK signaling pathway in colorectal cancer [1] [2].
Smiles
S(C=1SC(NC(NC2=CC=C(C(F)(F)F)C=C2)=O)=NN1)C=3C=C(NCCCN4CCOCC4)N=CN3
Molecular Formula
C21H23F3N8O2S2
Molecular Weight
540.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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