Sotuletinib dihydrochloride
Product Specifications
CAS Number
2222138-40-9
Target
C-Fms
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable CSF1-R inhibitor with an IC50 of 1 nM, promoting apoptosis in tumor cells and significantly restricting tumor growth in murine models, thereby proving useful in cancer and amyotrophic lateral sclerosis (ALS) studies [1].
Smiles
N(C=1SC=2C(N1)=CC=C(OC=3C=C(C(NC)=O)N=CC3)C2)[C@H]4[C@H](O)CCCC4.Cl.Cl
Molecular Formula
C20H24Cl2N4O3S
Molecular Weight
471.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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TA385132 100 µL
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