VU0029251
Product Specifications
CAS Number
330819-85-7
Target
Others, GluR
Related Pathways
Neuroscience, Others
Bioactivity
VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM. It also attenuates glutamate-induced calcium mobilization in HEK293 cell membranes that express rat mGluR5, demonstrating an IC 50 of 1.7 μM [1].
Smiles
CSC1=NC2=C(C3=C(CCC3)S2)C(N)=N1
Molecular Formula
C10H11N3S2
Molecular Weight
237.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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