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CK2-IN-9

Product Specifications

CAS Number

1461658-58-1

Target

Others, Casein Kinase, Wnt/beta-catenin

Related Pathways

Stem Cells, Metabolism, Others, Cytoskeletal Signaling

Bioactivity

CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter activity with an IC50 of 75 nM. In rats, it demonstrates low exposure (AUC=0.36 μM/h) and high clearance (CL=65 mL/min/kg) [1].

Smiles

C(#N)C1=C2N(C(NC3CC3)=CC(NC4=CC(NC(C)=O)=C(N(CCN(C)C)C)C=C4)=N2)N=C1

Molecular Formula

C23H29N9O

Molecular Weight

447.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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