CK2-IN-9
Product Specifications
CAS Number
1461658-58-1
Target
Others, Casein Kinase, Wnt/beta-catenin
Related Pathways
Stem Cells, Metabolism, Others, Cytoskeletal Signaling
Bioactivity
CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter activity with an IC50 of 75 nM. In rats, it demonstrates low exposure (AUC=0.36 μM/h) and high clearance (CL=65 mL/min/kg) [1].
Smiles
C(#N)C1=C2N(C(NC3CC3)=CC(NC4=CC(NC(C)=O)=C(N(CCN(C)C)C)C=C4)=N2)N=C1
Molecular Formula
C23H29N9O
Molecular Weight
447.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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