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VK-1727

Product Specifications

Target

Antifection, DNA

Related Pathways

DNA Damage/DNA Repair, Microbiology/Virology

Purity

0.98074

Bioactivity

VK-1727, a selective small molecule inhibitor of EBNA1, reduces the DNA binding activity of EBNA1 while simultaneously restricting the proliferation and metabolic activity of EBV-positive cells, it does so without influencing the viability of EBV-negative cells, thereby demonstrating specificity. VK-1727 is primarily employed in researchs that focus on multiple sclerosis, in which it serves as a tool compound to interrogate EBNA1-mediated mechanisms in disease-related processes.

Smiles

COC(C1=CC=CC(C#CC(C=C2)=CC=C2OC3CCOCC3)=C1C4=CC=C(C=CN5)C5=C4)=O

Molecular Formula

C29H25NO4

Molecular Weight

451.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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